Autoclicker

Can I use a autoclicker in wynn so my finger don't cramp like every 5 minute while grinding mobs.

 

From the Game & Forum Rules:
2. Macros

Macros are only allowed to be used to input a single 3-click spell command at a time or to automate chat commands such as the party system. Macros that loop or are designed to do anything else are not allowed as it gives you an unfair advantage. However, macros that loop melee attacks by keeping a mouse/keyboard button pressed down are allowed.

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An autoclicker that specifically loops melee attacks is allowed, as it is the same as placing a weight on the mouse or key.
The rest of the rules regarding legal macros are primarily used by game modifications such as Wynntils.